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Digitale Medien

IgE-positive epidermal Langerhans cells in allergic contact dermatitis lesions provoked in patients with atopic dermatitis (1990)

Sugiura, H. ; Uehara, M. ; Maeda, T.

Springer

Archives of dermatological research 282 (1990), S. 295-299

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Details

ISSN: 1432-069X

Schlagwort(e): Atopic dermatitis ; IgE ; Langerhans cells ; Dinitrochlorobenzene ; Atopic respiratory disease

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary To see whether or not IgE-bearing epidermal Langerhans cells are specific to skin lesions of atopic dermatitis (AD), we performed immunohistochemical and immunoelectron microscopic examinations of dinitrochlorobenzene (DNCB) contact dermatitis lesions provoked in uninvolved skin of eight patients with AD. In all of the eight examined, IgE-positive epidermal Langerhans cells were observed in the DNCB dermatitis lesions. Typical staining of anti-IgE was absent in the epidermis of normal-appearing skin of five patients with AD. Thus, it is likely that IgE positive epidermal Langerhans cells non-specifically occur in different eczematous diseases provoked in patients with AD.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00375722

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