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  • 1
    Electronic Resource
    Electronic Resource
    High-Speed Tools for Global Information Management. II. Specifications and Uses of the Transparent Query Language (TQL) (1998)
    Springer
    Journal of systems integration 8 (1998), S. 343-358 
    Details
    ISSN: 1573-8787
    Keywords: Transparent Query Language ; Mathematically Complete Language ; Philosophically Closed Language ; SOLID Retrieval/Processing System
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract This part, PART IIB [2], of the document “HIGH-SPEED TOOLS FOR GLOBAL INFORMATION MANAGEMENT. II. Specifications and Uses of the Transparent Query Language (TQL)” [1–6] contains the specifications for the operations that provide the arithmetic capabilities for Transparent Query Language. PART IIB references PART IIA [1] and PART IIC [3]. Concise definitions of Transparent Query Language terms, Conclusions and Acknowledgments are given in PART IIF [6].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008417304065
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  • 2
    Electronic Resource
    Electronic Resource
    High-Speed Tools for Global Information Management. II. Specifications and Uses of the Transparent Query Language (TQL) (1998)
    Springer
    Journal of systems integration 8 (1998), S. 359-377 
    Details
    ISSN: 1573-8787
    Keywords: Transparent Query Language ; Mathematically Complete Language ; Philosophically Closed Language ; SOLID Retrieval/Processing System
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract This part, PART IIC [3], of the document “HIGH-SPEED TOOLS FOR GLOBAL INFORMATION MANAGEMENT. II. Specifications and Uses of the Transparent Query Language (TQL)” [1–6] is a continuation of [2] and should be studied immediately after reading PART IIB [2]. It describes (i) the security system that can be easily invoked to deny unauthorized access to any item of information in any database; (ii) the special codes that can be used to specify virtually any degree of uncertainty; (iii) the registry numbers which terminate information paths; and (iv) the command structure for the Transportable Query Language. PART IIC references PART IIA [1], PART IIB [2], PART IID [4] and PART IIF [6]. Concise definitions of Transparent Query Language terms, Conclusions and Acknowledgments are given in PART IIF [6].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008469320904
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  • 3
    Electronic Resource
    Electronic Resource
    High-Speed Tools for Global Information Management. II. Specifications and Uses of the Transparent Query Language (TQL) (1998)
    Springer
    Journal of systems integration 8 (1998), S. 319-341 
    Details
    ISSN: 1573-8787
    Keywords: Transparent Query Language ; Mathematically Complete Language ; Philosophically Closed Language ; SOLID Retrieval/Processing System
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract In the six parts of the document “HIGH-SPEED TOOLS FOR GLOBAL INFORMATION MANAGEMENT. II. Specifications and Uses of the Transparent Query Language (TQL)” [1–6], the Transparent Query Language (TQL) that is the mathematical basis for the SOLID Retrieval/Processing System [7] is described and its use demonstrated. TQL is directly responsible for the speed, versatility, security and information/question-type independence of the SOLID System. It can be viewed as a Mathematically Complete (or Philosophically Closed) [8] data structure or content/context independent language capable of describing individual or classes of descriptors in any combination with any degree of specificity. The security system is easily used to prevent unauthorized access to any item in any file. TQL is sufficiently general to be used outside the context of information retrieval. It is capable of concisely representing and manipulating a wide variety of time dependent or static numeric and non-numeric information. The six parts of this document [1–6], are as follows. The first part, PART IIA [1], contains a review of the literature and then introduces the Transparent Query Language. It references PART IIB [2], PART IIC [3], PART IID [4], PART IIE [5] and PART IIF [6]. Concise definitions of Transparent Query Language terms, Conclusions and Acknowledgments are given in PART IIF [6]. Section III in PART IIA [1] contains information for converting citations of sections and subsections in the original document to their locations in the partitioned document.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008475419995
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  • 4
    Electronic Resource
    Electronic Resource
    High-Speed Tools for Global Information Management. II. Specifications and Uses of the Transparent Query Language (TQL) PART IID. Manipulation of Information Representations (1999)
    Springer
    Journal of systems integration 9 (1999), S. 5-28 
    Details
    ISSN: 1573-8787
    Keywords: Transparent Query Language ; Mathematically Complete Language ; Philosophically Closed Language ; SOLID Retrieval/Processing System
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract This part, PART IID [4], of the document “HIGH-SPEED TOOLS FOR GLOBAL INFORMATION MANAGEMENT. II. Specifications and Uses of the Transparent Query Language (TQL)” [1–6] is about normalization and manipulation of information representations. It references PART IIA [1], PART IIB [2] and PART IIC [3]. Concise definitions of Transparent Query Language terms, Conclusions and Acknowledgments are given in PART IIF [6].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008492103012
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  • 5
    Electronic Resource
    Electronic Resource
    High-Speed Tools for Global Information Management. II. Specifications and Uses of the Transparent Query Language (TQL) (1999)
    Springer
    Journal of systems integration 9 (1999), S. 29-53 
    Details
    ISSN: 1573-8787
    Keywords: Transparent Query Language ; Mathematically Complete Language ; Philosophically Closed Language ; SOLID Retrieval/Processing System ; Sequel (SQL) ; Relational Algebra ; QUEL ; Query-By-Example (QBE)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract In this part, PART IIE [5], of the document “HIGH-SPEED TOOLS FOR GLOBAL INFORMATION MANAGEMENT. II. Specifications and Uses of the Transparent Query Language (TQL)” [1–6] the conversion of queries coded in SQL, Relational Algebra, QUEL and Query-By-Examples (QBE) to TQL are demonstrated. PART IIE references PART IIA [1], PART IIB [2], PART IID [3] and PART IIF [6]. Concise definitions of Transparent Query Language terms, Conclusions and Acknowledgments are given in PART IIF [6].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008450419850
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  • 6
    Electronic Resource
    Electronic Resource
    High-Speed Tools for Global Information Management.II. Specifications and Uses of the Transparent Query Language (TQL) Part IIF. Additional Uses of TQL, Data Structures, Concise Definitions, Conclusions and Acknowledgments (1999)
    Springer
    Journal of systems integration 9 (1999), S. 55-71 
    Details
    ISSN: 1573-8787
    Keywords: Transparent Query Language ; Mathematically Complete Language ; Philosophically Closed Language ; SOLID Retrieval/Processing System
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract This part, PART IIF [6], concludes the document “HIGH-SPEED TOOLS FOR GLOBAL INFORMATION MANAGEMENT. II. Specifications and Uses of the Transparent Query Language (TQL)” [1–6]. It describes novel applications of TQL, the key data structures, and contains a dictionary of Transparent Query Language terms. PART IIF references PART IIA [1], PART IIB [2], PART IIC [3], PART IID [4], and PART IIE [5] and contains Conclusions and Acknowledgements.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008402503920
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  • 7
    Electronic Resource
    Electronic Resource
    NCI-navy medical oncology branch cell line data base (1996)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 63 (1996), S. 32-91 
    Details
    ISSN: 0730-2312
    Keywords: cell lines ; clinical correlation ; in vitro data ; polymorphic markers ; lung cancer ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The cell line data base described in this paper includes both clinical information about the patients from whom the cell line were derived and information about the in vitro analyses performed of the cell lines. The cell line data base has evolved as a part of a systematic effort by a research group at the NCI since 1976 to generate human cell lines as biological tools to study cancer and other diseases. The cell lines were generated from clinical specimens obtained as part of a series of Institutional Review Board-approved clinical protocols. The preponderance of the data is on lung cancer cell lines, though a broad range of other cancers are represented. A bank of over 300 human cell lines including cancer cell and in some instances autologous B-lymphoblastoid cells from the NCI-VA and NCI-Navy Medical Oncology Branch are reposited at the American Type Culture Collection. The cell lines are available for the research community. The entire data base is available on the American Type Culture Collection Web Site (///http://www.atcc.org/). © 1996 Wiley-Liss, Inc.This article is a US Government work and, as such, is in the public domain in the United States of America.
    Additional Material: 5 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240630505
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  • 8
    Electronic Resource
    Electronic Resource
    T-Cell lymphoma cell lines (HUT102 and HUT78) established at the National Cancer Institute: History and importance to understanding the biology, clinical features, and therapy of cutaneous T-cell lymphomas (CTCL) and adult T-cell leukemia-lymphomas (ATLL) (1996)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 63 (1996), S. 12-23 
    Details
    ISSN: 0730-2312
    Keywords: CTCL ; Sezary ; HTLV-I ; HIV ; IL-2 ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Efforts at the National Cancer Institute to generate continuous in vitro cultures from patients with mycosis fungoides and the Sezary syndrome, neoplasms with a mature T-helper phenotype, led to the establishment of two cell lines, HUT78 and HUT102. Further characterization of these cell lines led to the identification of the first human retrovirus, HTLV-1, in the HUT102 cells, and the clinical description of the syndrome of HTLV-1 associated acute T-cell leukemia/lymphoma; the serum antibody test to screen for this virus was developed from the serum of the patient from whom the cell line was derived. The HUT78 cell line was pivotal in the identification and characterization of the HIV retrovirus in that a subclone, H9, proved to be permissive for replication of HIV in vitro. Propagation of HIV in vitro in H9 cells allowed for the development of immunological reagents to screen blood supplies for the presence of the virus. Further biologic and molecular studies of these lines have led not only to a better understanding of the underlying diseases but also to the development of rational therapeutic approaches. © 1996 Wiley-Liss, Inc.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240630503
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  • 9
    Electronic Resource
    Electronic Resource
    Production of monoclonal antibodies against a cell surface concanavalin a binding glycoprotein (1979)
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 11 (1979), S. 563-577 
    Details
    ISSN: 0091-7419
    Keywords: plasma membrane ; lectin receptors ; affinity chromatography ; membrane proteins ; hybridoma ; monoclonal antibody ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Concanavalin A-binding (Con A)-binding cell surface glycoproteins were isolated, via Con A-affinity chromatography, from Triton X-100-solubilized Chinese hamster ovary (CHO) cell plasma membranes. The Con A binding glycoproteins isolated in this manner displayed a significantly different profile on sodium dodecyl sulfate-polyacrylamide gels than did the Tritonsoluble surface components, which were not retarded by the Con A-Sepharose column. [125I]-Con A overlays of the pooled column fractions displayed on sodium dodecyl sulfate-polyacrylamide gel electro-phoresis (SDS-PAGE) demonstrated that there were virtually no Con A receptors associated with the unretarded peak released by the Con A-Sepharose column, whereas the material which was bound and specifically eluted from the Con A-Sepharose column with the sugar hapten α-methyl-D-mannopyranoside contained at least 15 prominent bands which bound [125I]-Con A.In order to produce monoclonal antibodies against various cell surface Con A receptors, Balb/c mice were immunized with the pooled Con A receptor fraction. Following immunization spleens were excised from the animals and single spleen cell suspensions were fused with mouse myeloma P3/X63-Ag8 cells. Numerous hybridoma clones were subsequently picked on the basis of their ability to secrete antibody which could bind to both live and glutaraldehyde-fixed CHO cells as well as to the Triton-soluble fraction isolated from the CHO plasma membrane fraction. Antibody from two of these clones was able to precipitate a single [125I]-labeled CHO surface component of ∼265,000 daltons.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jss.400110414
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  • 10
    Electronic Resource
    Electronic Resource
    The amino- and carboxyl-terminal sequence of bovine rhodopsin (1977)
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 6 (1977), S. 559-570 
    Details
    ISSN: 0091-7419
    Keywords: rhodopsin ; rod cell membrane ; limited proteolysis ; phosphorylation site ; amino-terminal ; carboxy-terminal ; carbohydrate attachment ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The amino terminus of bovine rhodopsin is blocked and has the sequence x-Met-Asn(CHO)-Gly-Thr-Glu-Gly-Pro-Asn-Phe-Tyr-Val-Pro-Phe-Ser-Asn(CHO)-Lys-Thr-Gly-Val-Val-Arg, where CHO represents sites of carbohydrate attachment. The carboxyl-terminal sequence of rhodopsin is Val-Ser-Lys-Thr-Glu-Thr-Ser-Gln-Val-Ala-Pro-Ala. Upon short-term digestion of rod outer segment (ROS) membranes with thermolysin, opsin (∼ 35,000 daltons) is converted to a membrane-bound fragment O′ (∼ 30,500 daltons) and 2 peptides containing 12 amino acids are released from the carboxyl terminus of rhodopsin into the supernatant. Upon long-term digestion of ROS with thermolysin, opsin and O′ are replaced by the membrane-bound fragments F1 (∼25,000 daltons), and F2 (∼9,500 daltons). When 32P-ROS are digested, F2 carries the 32P. Both O′ and F1 contain the amino-terminal glycopeptide.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jss.400060409
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