ISSN:
0138-4988
Keywords:
Life Sciences
;
Life Sciences (general)
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Process Engineering, Biotechnology, Nutrition Technology
Notes:
The production of genetically engineered antibodies in Escherichia coli is now possible. The resulting fragments are completely functional and have antigen binding constants industinguishable from the natural antibody. This article summarizes the biochemical basis of this newly developed technology and the properties of the resulting fragments. It is likely that this technology will have an important role in antibody production for technical, medical and research uses. Screening of E. coli libraries may mount a challenge to traditional antibody production methods.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/abio.370110509
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