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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 165 (1976), S. 297-306 
    ISSN: 1432-0878
    Keywords: Pineal gland ; Mole ; Yellow-orange autofluorescent material ; Subcommissural organ
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Une étude de la glande pinéale de la Taupe, animal vivant toujours dans une obscurité complète, a été entreprise selon la technique de fluorescence décrite par Falck et al. (1962). Une importante innervation catécholaminergique a été démontrée tandis que la fluorescence jaune — caractéristique des indoleamines-n'a pas été observée. Après omission du traitement par la formaldehyde, de très nombreuses cellules contenant du material autofluorescent (jaune-orange) furent observées. La nature et la fonction de ce material autofluorescent est discutée.
    Notes: Summary The pineal gland of the mole, a mammal which lives in permanent darkness, has been studied using fluorescence histochemistry. An extensive catecholaminergic innervation is demonstrated. A yellow formaldehyde-induced fluorescence, characteristic of indoleamines, was not observed. If formaldehyde vapour treatment was omitted in the procedure, numerous cells containing yellow-orange autofluorescent material could be shown. The nature and possible function of this material is discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 95 (1978), S. 287-294 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The potent tumor promoter tetradecanoyl phorbol acetate (TPA) induces early changes in ion movements analogous to those induced by prostaglandins E1 and F2α. Among the earliest changes induced by TPA is a significant increase in 32Pi incorporation within 15 minutes incubation of TPA (10-8-10-6 M) with post-confluent Swiss 3T3 mouse embryonic fibroblasts. Similarly, the active phorbol ester homolog 4-;β-;OH phorbol didecanoate but not the inactive stereoisomeric 4-β-OH phorbol didecanoate stimulated 32Pi incorporation. Also, TPA at the above concentrations stimulated 86Rb+ influx shortly after administration. Both fluxes were ouabain-sensitive in accord with the idea that an early effect of TPA is to alter (Na+ + K+)-ATPase activity. Further, prostaglandin E1 (10-7-10-6 M) and prostaglandin F2α (3 × 10-9-10-7 M) caused a similar stimulation of 86Rb+ and 32Pi uptake. The finding that water-soluble prostaglandin F2α also exhibited stimulatory effects indicated that those hormone-induced responses are not mediated by solvent interactions. The similar responses of phorbol esters and prostaglandin derivatives suggests that phorbol esters and prostaglandin derivatives may act at common membrane sitesThe finding that stimulatory effects were observed at discrete times in the logarithmic phase of growth suggests that the activation of membrane receptors may be cell-cycle dependent.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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