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  • Life and Medical Sciences  (6)
  • 1
    Electronic Resource
    Electronic Resource
    Ingestion of particulate matter by the outer surface cells of the mollusc mantleThis investigation was supported (in part) by grant DE-01825 from the N.I.D.R., U.S.P.H. Service. (1967)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 122 (1967), S. 139-145 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A study of the ingestion of particulate matter from the pallial space located between the shell and the outer surface of the mantle of Isognomon alatus and Pinctada radiata was undertaken with the aid of the electron microscope. For this purpose colloidal thorium dioxide (thorotrast) was introduced into the pallial space for periods of 1-5 days after which time the mantle was excised and prepared for examination with the electron microscope. After 24 hours thorotrast micelles were observed in the pallial space, on the surface of the microvilli, in small pinocytotic vesicles between the bases of the microvilli, in vacuoles undergoing coalescence and finally in large dense bodies (lysosomes). Amoebocytes in the pallial space also participate in the removal of particulate matter in a manner similar to that described for the surface epithelium. During active ingestion the Golgi apparatus changes from a vesicular to a lamellar form. The method of ingestion observed in the surface epithelia and the amoebocytes is similar to the ingestion of protein and other particulate material reported for a variety of vertebrate tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051220206
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Correlation between tetracycline binding and mineralization in dentin and enamelThis investigation was supported (in part) by grant DE-01825-03, from the N.I.D.R., U.S.P.H. Service. (1965)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 153 (1965), S. 141-147 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Experiments were conducted on the incisor of young rats to show (1) the precise areas and manner in which the tetracycline fluorophore combines with dentin and enamel and (2) the relation between the tetracycline localization and mineralization. For the objectives mentioned above rats were injected with tetracycline and a combination of tetracycline and Ca45. Detailed examination of the teeth of specimens injected with tetracycline show a rapid uptake and localization of fluorophore in areas undergoing mineralization. Areas adjacent to the increments undergoing mineralization also reveal the presence of the fluorophore, but to a lesser extent. Comparison of the same area of the tooth injected with tetracycline and Ca45 show that the fluorophore is localized exclusively in areas undergoing mineralization, and to a lesser extent in adjacent, incompletely mineralized regions.Despite the fact that our observations have demonstrated the avidity tetracycline exhibits for mineralizing and recently mineralized areas of dentin and enamel, we have not been able to exclude the possibility that the fluorophore may combine with the organic matrix of these tissues as well as the mineral component.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091530204
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Further discussion of otolith mineralization (1980)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 197 (1980), S. 377-378 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091970313
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    An electron microscope study of crystal calcium carbonate formation in the mouse otolith (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 193 (1979), S. 233-241 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ultrathin sections of the developing otolith of mouse fetuses 15.5 days to 20 days after birth were observed with the aid of the electron microscope.The first step of otolith formation is an aggregation of organic clusters observed in the sacculus of the 15.5-day fetus. These organic structures are modified and assume a hexagonal shape in the 17.5-day fetus. The unmineralized stages of the otolith referred to as the preotolith, serve as the template for future development.One day after birth, at either end of the preotolith, minute tube-like structures develop in which needle-shaped crystallites are initiated. Crystallites continue to develop throughout the hexagonal template which give rise to a structure containing many regularly arranged needle-shaped crystallites. Based on the present observations, the mouse otolith is considered a multi-iso-oriented crystal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091930205
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    The formation and mineralization of dentinThis investigation was supported (in part) by grant DE-01825 from the N.I.D.R., U.S.P.H. Service. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 156 (1966), S. 303-323 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Observations were conducted at the light and electron microscope level of the formation and mineralization of dentin. At the light level it was shown that predentin is made up of the odontoblast process, collagen fibers and a ground substance. As mineralization occurs, the fibers tend to condense and thicken in areas adjacent to the odontoblast process. Fibers continue to invade the developing matrix and, as in early dentinogenesis, they appear at all times to be derived from the pulp.At the E.M. level the significant observations made in reference to dentin formation consist of the identification of granular masses appearing in the interfibrillar spaces initially in the region of the dentino enamel junction. Histochemical tests at the E.M. level demonstrated that the odontoblasts elaborate an acid mucopolysaccharide which concentrates in granules at the base of the odontoblast process. Subsequently these granules are extruded into the matrix where the polysaccharide becomes concentrated in the interfibrillar spaces and to come extent on the collagen fibers. The onset of mineralization occurs in the patches of mucopolysaccharide, later also on the fibers. It appears that the presence of an acid mucopolysaccharide is a prerequisit for mineralization in the dental matrix.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091560306
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    The fine structure of the human peridental ligamentThis investigation was supported (in part) by grant DE-0125, from the N.I.D.R., U.S.P.H. Service. (1968)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 162 (1968), S. 313-325 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: An electron microscope study was made of the human peridental ligament of the young adult. Examination of several cells which occur in this site exhibit a marked variation in number and distribution of organelles. The fibrous components made up chiefly, if not entirely, of collagen fibers averaged 600 Å in diameter. These fibers usually referred to as principal fibers show an arrangement both in the peridental space proper and also at the surface of the root of a marked irregularity, more so than can be ascertained at the optical level. Our study shows that the arrangement of the principal fibers is more complex than previously described and further that many of the diverse cells present in the peridental space are in an active functional state indicative of the dynamic potential they possess in reference to fibrilogenesis, cementogenesis and osteogenesis in this area.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091620306
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    Paper (German National Licenses)
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