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Digitale Medien

Initial clinical experience of lorcainide (Ro 13-1042), a new antiarrhythmic agent (1978)

Cocco, G. ; Strozzi, C.

Springer

European journal of clinical pharmacology 14 (1978), S. 105-109

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Details

ISSN: 1432-1041

Schlagwort(e): Lorcainide ; antiarrhythmic agent ; ventricular arrhythmia

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Summary Lorcainide is a promising antiarrhythmic agent that belongs to the class of local anesthetics. It was tested in 7 patients with malignant ventricular arrhythmias that were resistant to other antiarrhythmic agents. Lorcainide was effective in all cases (complete disappearance of arrhythmias in 6 cases and more than 50% disappearance in the 7th case), and the tolerance was within acceptable limits. The drug was effective at rest, as assessed by 24-h dynamic electrocardiographic monitoring, and during physical exercise. Longer studies with more patients are warranted, since the drug appears to be a promising antiarrhythmic agent.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00607440

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