ISSN:
1432-1432
Keywords:
MS2 RNA
;
Codon-anticodon
;
Choice of code words
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary The non-random distribution of degenerate code words in Bacteriophage MS2 RNA can be explained partially by considerations of the stability of the codon-anticodon complex in prokaryotic systems. Supporting this hypothesis we note that wobble codons are positively selected in codons having G and/or C in the first two positions. In contrast, wobble codons are statitically less likely in codons composed of A and U in the first two positions. Analyses of nucleotides adjacent to 5′ and 3′ ends of codons indicate a nonrandom distribution as well. It is thus likely that some elements of RNA evolution are independent of the structural needs of the RNA itself and of the translated protein product.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01733262
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