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  • 1
    Electronic Resource
    Electronic Resource
    Starvation in yeast increases non-adaptive mutation (1999)
    Springer
    Current genetics 35 (1999), S. 77-81 
    Details
    ISSN: 1432-0983
    Keywords: Key words Adaptive mutations ; 6-N-hydroxylaminopurine ; Saccharomyces cerevisiae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The frequency of reversion in a histidine-requiring mutant of Saccharomyces cerevisiae increases about ten-fold in stationary cells during histidine starvation. Histidine starvation enhances a similar frequency of reversion in a tryptophan-requiring mutant. Starvation, therefore, enhances mutation frequencies in a non-adaptive manner. The base analogue 6-N-hydroxylaminopurine (HAP) added prior to plating on medium with limited histidine strongly increases reversion of the histidine mutant. HAP-induced reversion increases further in stationary starving cells with the same kinetics as that which increases spontaneous reversion. Adding HAP to the stationary starving cells does not produce any effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002940050435
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    MTDSC Calibration Dependence of the Instrumental Response Upon Experimental Conditions (1999)
    Springer
    Journal of thermal analysis and calorimetry 56 (1999), S. 699-715 
    Details
    ISSN: 1572-8943
    Keywords: calibration ; heat capacity ; MTDSC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The heat capacity calibration ‘constants’ of a commercial MTDSC system (TA 3100) were determined in a variety of experimental conditions. For a given modulation frequency, the calibration constants are the same within a few percents for different temperatures, and over a wide range of modulation amplitudes and scan rates. This variation decreases below 1% if hidden instrumental constraints are taken into account, which are related with the capability of the control system to achieve the desired temperature program. On the other hand, the calibration constant changes substantially with the period, and takes anomalously high values for the short modulation periods (20+40 s). Rules to optimize the accuracy of the system are given.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1010141719713
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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