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α1-Antitrypsin polymorphism in Malaysian Macaca irus (1977)

Kueppers, F. ; Ganesan, J.

Springer

Biochemical genetics 15 (1977), S. 817-823

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ISSN: 1573-4927

Keywords: α1-antitrypsin types ; serum trypsin inhibiting activity ; Malaysian Macaca irus

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract α1-Antitrypsin types were determined in 200 individual specimens of Malaysian Macaca irus. We found the pattern B in 76 samples, BC in 116, and C in 8. Assuming that these patterns are determined by codominant alleles at one locus, this distribution constitutes a significant (P〈0.001) deviation from Hardy-Weinberg equilibrium, because of an excess of BC and low prevalence of C. We found no clear evidence for the presence of α1-antitrypsin deficiency comparable to the situation in man.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00483978

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