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  • Cell & Developmental Biology  (3)
  • Polymer and Materials Science  (3)
  • Metabolism  (2)
  • 1
    ISSN: 1439-6327
    Keywords: Key words Carbohydrate ; Dehydration ; Metabolism ; Recovery ; Thermoregulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Recovery from prolonged exercise involves both rehydration and replenishment of endogenous carbohydrate stores. This study examined the influence of drinking a carbohydrate-electrolyte solution on short-term recovery and subsequent exercise capacity in a warm environment. Thirteen healthy male volunteers completed two trials, at least 7 days apart. On each occasion subjects performed an initial treadmill run at 60% of maximal oxygen uptake (VO2max), for 90 min or until volitional fatigue (T1), in a warm environment (35 °C, 40% relative humidity, RH). Volitional ingestion of water was permitted during each of the exercise trials. During a subsequent 4-h recovery period (REC) subjects consumed either a 6.9% carbohydrate-electrolyte solution (CES) or a sweetened placebo (P), in a volume equivalent to 140% of body mass loss. Following REC, subjects ran to exhaustion at the same %VO2max in order to assess their endurance capacity (T2). Mean (SEM) run times during T1 did not differ between the CES [74.8 (4.6) min] and P [72.5 (5.2) min] trials. Body mass was reduced (P 〈 0.01) by 1.9 (0.2)% (CES) and 1.7 (0.2)% (P), and plasma volume (P 〈 0.01) by 6.0 (0.9)% (CES) and 5.4 (1.0)% (P) during the T1 trials. During REC 2006 (176) ml and 1830 (165) ml of fluid was ingested, providing 138 (12) g and 0 g of carbohydrate in the CES and P trials, respectively. Prior to T2, plasma volume and net fluid balance were similarly restored [CES +58 (26) g; P −4 (68) g] in both trials. During T2 the exercise duration was longer (P 〈 0.01) in the CES compared to the P trial [CES 60.9 (5.5) min; P 44.9 (3.0) min]. Thus, provided that an adequate hydration status is maintained, inclusion of carbohydrate within an oral rehydration solution will delay the onset of fatigue during a subsequent bout of prolonged submaximal running in a warm environment.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 39 (1978), S. 7-16 
    ISSN: 1439-6327
    Keywords: Exercise ; Carbohydrate ; Metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Four subjects were studied during exercise at 50% of maximum oxygen uptake after a normal diet, after a low carbohydrate (CHO) diet following exercise-induced glycogen depletion, and after a high CHO diet. This regime has previously been shown to cause changes in the amount of glycogen stored in the exercising muscles. Metabolic and respiratory parameters were measured during the exercise. The respiratory exchange ratio, blood lactate, blood pyruvate, blood glucose and plasma triglycerides were lower than normal following the low CHO diet and higher than normal following the high CHO diet. Plasma free fatty acids and plasma glycerol were higher than normal after the low CHO diet and lower than normal after the high CHO diet. The contribution of CHO to metabolism was less than normal after the low CHO diet and greater than normal after the high CHO diet. The altered availability of FFA does not appear to be a result of the variations in the blood lactate content.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Polymers for Advanced Technologies 5 (1994), S. 79-89 
    ISSN: 1042-7147
    Keywords: Copolymers bropylene-7 methyl 1-6 octadiene ; Sulfonation ; Ionomers aggregation state ; Mechanical properties ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Polypropylene ionomers have been prepared by sulfonation of copolymers of propene and 7 methyl, 1-6 octadiene, followed by neutralization to cesium salts. Both WAXS and SAXS were used to study the morphology of the samples, while their thermal properties were studied by DSC and their mechanical properties by DMTA. The sulfonation process is shown to cause a further drop in crystallinity in addition to the effect of comonomer incorporation. Ion clustering is observed when the extent of sulfonation is high enough, the limit being dependent on the copolymer composition. The ion pairs which are not incorporated into the cluster cause a small-angle upturn in the WAXS pattern. The mechanical properties are strongly affected by the drop in crystallinity, but may be partly recovered due to ion clustering. No disruption of the ion clusters is observed before thermal decomposition of the polymer.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 128 (1986), S. 105-112 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Stimulation of cultured rabbit endometrial cells by one of the rabbit endometrial cell culture proliferation factors, prostaglandin F2α (PGF2α), resulted in a very rapid increase in the intracellular levels of [3H]-inositol triphosphate (IP3), [3H]-inositol biphosphate (IP2), and [3H]-inositol monophosphate (IP1) in cells prelabeled with [3H]-inositol. These increases in inositol phosphate levels were detected in periods of stimulation as short as 30 seconds, reached a maximum by 1 1/2-2 min and declined to control levels by 6-10 min. The stimulation was dose-dependent with maximal increases observed near 10-6 M PGF2α. The cholinergic agent, carbachol, also led to time and dose-independent increases in IP3. Lithium, cadmium, silver, copper, and zinc ions had no effect either on the breakdown of IP3 or on the accumulation of IP1. In contrast, vanadate at 10-6 or 10-5 M did lead to a decrease in the breakdown of IP1 and a concomitant increase in IP1, IP2, and IP3. PGF2α was found previously to induce an increase in rabbit endometrial cell DNA synthesis which was inhibited by concomitant or prior addition of prostaglandin E1 (PGE1). PGE1, in a dose-dependent manner, was found to inhibit the observed IP3 increase by PGF2α at 1 1/2 min of stimulation. PGF2α treated and control cultures did not differ in cAMP or cGMP levels, cellular 45Ca uptake, nor cellular 22Na uptake. We propose that IP3 may be one of the intracellular messenger(s) synthesized following the treatment of rabbit endometrial cell cultures with the proliferation agent PGF2α and that it may play a crucial role with cAMP in growth regulation.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 130 (1987), S. 292-300 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: We have hypothesized that two of the endogenously synthsized endometrial prostaglandins (PGs), prostaglandin F2α (PGF2α), and prostaglandin E1 (PGE1), play a regulatory role in growth control of the rabbit endometrium. PGF2α increases DNA synthesis and PGE1 inhibits that effect. Primary cultures of rabbit endometrial cells were used to examine the possible role of these PGs in the mechanism of action of 17β-estradiol on DNA synthesis. Towards this end, binding, second messenger and DNA synthesis experiments were performed. 17β-estradiol stimulation restulted in a time dependent (optimal: approximately 6 h) and 17β-estradiol concentration dependent (optimal: approximately 10-7 M 17β-estradiol in phenol red-containing medium) increase in [3H]PGF2α binding. Scatchard type analysis of the binding data revealed an increase in receptor number while the receptor affinity for [3H]PGF2α remained the same as in the control treated cultures. This 17β-estradiol stimulated increase in PGF2α receptor allowed a suboptimal concentration of PGF2α (10-9M) to increase intracellular levels of inositol polyphosphates, while by itself this concentration of PGF2α caused no significant change in intracellular inositol polyphosphate levels. 17β-estradiol, alone among the several studied steroid hormones, could increase [3H]PGF2α binding. Proliferation studies revealed that, in these primary cultures of rabbit endometrium, 17β-estradiol could increase DNA synthesis but not in the presence of indomethacin, unless PGF2α was addd to the medium at a concentration (10-9M) near or above what is normally accumulated in the medium by these cultures. In the absence of 17β-estradiol stimulation, addition of these same low concentrations of PGF2α had no effect on DNA synthesis. Apparently, through its effect on the PGF2α receptor, 17β-estradiol enhances the PGF2α stimulated DNA synthesis response approximately 100 fold. The DNA synthesis inducd by 17β-estradiol can be inhibited by PGE1, as can PGF2α-induced DNA synthesis. We propose that 17β-estradiol may be mediating its mitogenic effect through an alteration of the prostglandin agonist:antagonist control of proliferation in rabbit endometrial cultures. In additon we suggest that, if 17β-estradiol acts to increase PGF2α receptors as part of its mode of action, this may be of importance in other tissues possessing both prostaglandin and 17β-estradiol receptos.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 28 (1990), S. 1979-1986 
    ISSN: 0887-6266
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Block copolymers consisting of long styrene midblocks and much shorter 4-vinyl pyridine end-blocks were quaternized with n-iodo alkanes (2 ≤ n ≤ 10) to give block ionomers of a novel architecture. The name “bottlebrush” seems appropriate for these materials. A preliminary investigation of the morphology of these systems, prepared by in situ quaternization, is reported here. The morphology is dependent on both the length of the iodo alkane and the relative sizes of the blocks. Even with identical sample histories, two distinct morphologies are seen. One of these is characterized by a single broad SAXS peak, while the other shows a much narrower peak and higher-order features. The latter morphology is associated with the higher ionic to nonionic ratios and long side chains.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Electron Microscopy Technique 1 (1984), S. 311-312 
    ISSN: 0741-0581
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Natural Sciences in General
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0360-6384
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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