Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Microalbuminuria  (2)
  • Taste hairs  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Chemosensory control of pollen ingestion in the hoverfly Eristalis tenax by labellar taste hairs (2000)
    Springer
    Journal of comparative physiology 186 (2000), S. 193-203 
    Details
    ISSN: 1432-1351
    Keywords: Key wordsEristalis tenax ; Pollen ; Taste hairs ; Contact chemoreception ; Proline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The labellar gustatory system of the dronefly Eristalis tenax L. (Syrphidae; Diptera) that enables the fly to discriminate between pollen and nectar is investigated, and the triggering of pollen ingestion is examined. In behavioural preference tests, exhaustively extracted pollen of the sunflower Helianthus annuus is consumed in smaller amounts than untreated pollen, indicating that water-soluble substances are important for acceptance. Dry pollen is preferred over moist pollen in which the grains stick together, suggesting that mechanical properties of the pollen also play a role in its sensory assessment. Electrophysiological studies of the labellar taste hairs reveal that aqueous extracts of pollen (2% w/v) stimulate the salt receptor cell, but not the sugar receptor cell. The response of the water receptor cell remains the same as to pure water (or standard electrolyte, 10 mmol · l−1 KCl). Of the 20 amino acids tested, the salt cell is sensitive only to proline in a submillimolar range. Behavioural experiments support the electrophysiological findings. When KCl is applied at concentrations eliciting salt-cell spike frequencies equal to those produced by pollen extract (which is often accepted), the water receptor cell is inhibited and a pronounced rejection behaviour occurs. This rejection of concentrated salt solution in Eristalis is therefore mainly mediated by the inhibition of the water cell.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003590050019
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Reduced glomerular filtration rate and cardiovascular damage in diabetes: a key role for abnormal albuminuria (1992)
    Springer
    Acta diabetologica 29 (1992), S. 201-213 
    Details
    ISSN: 1432-5233
    Keywords: Abnormal albuminuria ; ACE-inhibition ; Hypertension ; Microalbuminuria ; Diabetic nephropathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There is general agreement that a fall rate in glomerular filtration rate (GFR) is the principal endpoint in diabetics with renal disease, and that abnormal albuminuria (including microalbuminuria) is an important intermediate end-point. The relative roles of blood pressure (BP) elevation and abnormal albuminuria in the prediction and genesis of renal disease are a matter of debate, and are further analysed in this paper. New studies show that neither genetic predisposition to hypertension (parental BP) nor parental abnormal albuminuria can be used to predict renal disease in patients with type 1 (insulin-dependent) diabetes. However, parental predisposition to proteinuria seems to be important to certain types of patients with type 2 (non-insulin-dependent) diabetes. Cross-sectional as well as follow-up studies document that GFR is generally well preserved in microalbuminuria (in both type 1 and type 2 patients), while the transition to clinical proteinuria is associated with a decline in GFR. Thus, prevention of overt proteinuria is important in clinical trials in microalbuminuric patients. In type 1 diabetes clear ultrastructural changes have been documented with microalbuminuria and a good correlation between abnormal albuminuria and structural damage is seen. Structural damage in normo- and microalbuminuric patients correlates poorly with BP. New studies in type 1 diabetes document that microalbuminuria (but not elevated BP) predicts not only clinical diabetic nephropathy but also end-stage renal failure and mortality. In type 2 diabetes microalbuminuria is the strongest predictor of mortality, whereas BP elevation is not a predictor. Several studies now document that antihypertensive treatment, especially with inhibitors of angiotensin converting enzyme, is able to reverse or reduce abnormal albuminuria, even in non-hypertensive type 1 patients, and possibly preserve GFR. Therefore, microalbuminuria may be the main indicator for starting antihypertensive treatment in these patients. With respect to organ damage in the retina, abnormal albuminuria is an important indicator of the risk of severe diabetic retinopathy. BP elevation seems not to be an initiating factor, but rather aggravates established retinopathy. Left ventricular hypertrophy has a stronger correlation with BP elevation than normoalbuminuria, suggesting that left ventricular hypertrophy is at least partially a phenomenon secondary to elevated BP in diabetic patients with abnormal albuminuria. Generally, abnormal albuminuria is a strong indicator of cardiovascular renal damage in diabetic patients and in most organs is a stronger factor than elevated BP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00573489
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Acute renal effects of angiotensin converting enzyme inhibition in microalbuminuric type 1 diabetic patients (1993)
    Springer
    Acta diabetologica 30 (1993), S. 149-153 
    Details
    ISSN: 1432-5233
    Keywords: Angiotensin converting enzyme inhibition ; Microalbuminuria ; Renal haemodynamics ; Type 1 diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The renal effects of intravenous injection of 40 mg enalapril were investigated in 16 normotensive microalbuminuric type 1 (insulin-dependent) diabetic patients. After enalapril the following changes were observed: fractional albumin clearance (Θ Alb) decreased from 9.9 (3.0–23.8) to 8.2 (2.0–18.3)×10−6 (2P〈0.01); filtration fraction (FF) decreased from 0.260 (0.225–0.312) to 0.253 (0.190–0.297) (2P〈0.01); renal plasma flow (RPF) increased from 565 (411–690) to 623 (449–785) (2P〈0.01); and glomerular filtration rate (GFR) remained stable at 149 (128–181) versus 150 (124–185) ml · min−1 (NS). These values were unchanged after placebo (n=8), except for RFP which decreased from 606 (401–701) to 559 (381–677) ml · min−1 (2P〈0.05) and GFR which was reduced from 148 (111–173) to 138 (111–167) (2P〈0.05). A reduction in mean blood pressure from 94 (87–103) to 89 (79–101) mmHg (2P〈0.05) was found in the enalapril group and a minor reduction in the placebo group from 97 (83–106) to 96 (81–104) mmHg (2P〈0.05) was also noted. The relative changes in systolic blood pressure in the enalapril group correlated with changes in Θ Alb (Spearman'sr=0.66, 2P〈0.02) and FF (r=0.53, 2P〈0.05). Acute inhibition of angiotensin converting enzyme does not reduce the pathological hyperfiltration in these patients and a reduction in Θ Alb and FF can not be dissociated from the reduction in blood pressure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00572859
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Die Feinstruktur der tarsalen Schmeckhaare der Fliege Phormia terraenovae Rob.-Desv. (1971)
    Springer
    Cell & tissue research 117 (1971), S. 419-442 
    Details
    ISSN: 1432-0878
    Keywords: Taste hairs ; Insects ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Die Schmeckhaare der Fliege Phormia terraenovae enthalten fünf Rezeptorzellen (vier Kontaktchemo- und eine Mechanorezeptorzelle), die von zwei Hüllzellen unter Aussparung von Lymphräumen („Vakuole“) umgeben sind. Die Rezeptorzellen gliedern sich in Axon, Zellkörper und Dendrit, der aus Innenglied, Übergangsabschnitt und Außenglied besteht. Der Übergangsabschnitt hat die 9+0-Struktur der modifizierten Cilien mit zwei Basalkörpern. Im Plasma der Außenglieder sind nur Mikrotubuli zu erkennen. Die Außenglieder der Kontaktchemorezeptoren ziehen durch die röhrenförmige Dendritenscheide und den Kanal I des Haarschafts bis zu einem Porus in der Haarspitze, durch den sie mit den Schmeckstoffen in Kontakt kommen (Ort der Primärprozesse). Das Außenglied der Mechanorezeptorzelle enthält einen tubulären Körper und setzt an der Haarbasis an. Die Hüllzelle II (tormogene Zelle) bildet zum großen Sensillenlymphraum hin ein stark gefaltetes Membransystem aus. Der Feinbau wird in Beziehung zur Funktion der Schmeckhaare gesetzt.
    Notes: Summary The tarsal taste hairs of the blowfly contain five receptor cells: four contact chemoreceptors and one mechanoreceptor. These cells are surrounded concentrically by two sheath cells with fluid-filled spaces (“vacuoles”) between them. The receptor cell parts are the axon, the cell body, and the dendrite. The latter has an inner segment, a transitional region, and an outer segment. The transitional region shows the 9+0 configuration of a modified cilium with two basal bodies. In the outer segment only microtubules are found. The outer segments of contact chemoreceptors pass through the tube-like dendrite sheath, then through “canal I” of the hair shaft, to reach the pore at the tip of the hair. The outer segment of the mechanoreceptor contains a “tubular body” and terminates at the hair base. The “sheath cell II” (tormogene cell) forms a folded membrane system toward the main liquor space. The fine structure of the tarsal taste hairs is discussed in relation to their function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00324812
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...