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  • 1
    Electronic Resource
    Electronic Resource
    Activation of chloride conductance induced by potassium in tracheal epithelium (1988)
    Springer
    Pflügers Archiv 411 (1988), S. 252-258 
    Details
    ISSN: 1432-2013
    Keywords: Potassium depolarization ; Chloride conductance ; Ion fluxes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of partial replacement of bathing solution sodium by potassium on potential difference, conductance and ion transport of canine tracheal epithelium were studied in Ussing chambers. Whereas up to 100 mmol/l mucosal K+ had no effect, raised serosal [K+] induced a concentration dependent decrease in transepithelial potential difference and increase in conductance. When serosal K+ was 100 mmol/l, the potential difference fell 30 mV to 1.1±1.0 mV and conductance rose 4.5 mS/cm2 to 6.6 ±0.9 mS/cm2. Seventy-five percent of the K+ induced conductance required Cl− (120 mmol/l) in the luminal bathing solution. Unidirectional Cl− fluxes were increased by raised serosal K+ but14C-mannitol permeability was unchanged. The increased unidirectional Cl− flux induced by high K+ exposure was inhibited by luminal exposure to diphenylamine-2-carboxylic acid (DPC) or other chloride channel blockers, but was not inhibited by loop diuretics. These results suggest that in the presence of 100 mmol/l serosal K+ the transcellular chloride conductance of tracheal epithelium was increased. Increased chloride conductance of the apical cell membrane contributed to the raised transcellular permeability, but the route across the basolateral cell membrane was not identified.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00585111
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Exact minimum-time control of a distributed system using a traveling wave formulation (1992)
    Springer
    Journal of optimization theory and applications 73 (1992), S. 149-167 
    Details
    ISSN: 1573-2878
    Keywords: Minimum-time control ; time-optimal control ; distributed parameter systems ; traveling waves
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this paper, the minimum-time control problem for rest-to-rest translation of a one-dimensional second-order distributed parameter system by means of two bounded control inputs at the ends is solved. A traveling wave formulation allows the problem to be solved exactly, i.e., without modal truncation. It is found that the minimum-time control is not bang-bang, as it is for systems with a finite number of degrees of freedom. Rather, it is bang-off-bang, where a period of control inactivity in the middle of the control time interval is required for synchronization with waves propagated through the system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00940083
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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