ISSN:
1434-1948
Keywords:
Monooxamide
;
Amide hydrolysis
;
Cobalt(III)
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The reactions of sodium monooxamide (H2NCOCO2Na) with trans-[Co(en)2Cl2]Cl, trans-[Co(3,2,3-tet)Cl2]Cl (3,2,3-tet = 1,5,8,12-tetraazadodecane), cis-α-[Co(trien)Cl2]Cl and [Co(tren)Cl2]Cl result in the formation of [Co(en)2(ox)]Cl · 4H2O (1), cis-β-[Co(3,2,3-tet)(ox)]Cl· 4 H2O (2), cis-α-[Co(trien)(ox)]Cl · 2 H2O (3), and [Co(tren)(ox)](ClO4) · 0.5 H2O (4) respectively, implying a hydrolytic cleavage of the amide bond. [Co(tren)(O,O′-oxam)]Cl2 · 2 H2O (5) (oxam = H2NCOCO2-) and p-[Co(tren)(NH3)(O-oxam)]Cl2 (6) have also been prepared in order to give mechanistic information for the hydrolysis of monooxamide. Crystal structures of the products are reported and possible pathways for the hydrolysis reactions are discussed.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
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