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    ISSN: 1432-1238
    Keywords: Key words Cardiac output ; Complications ; Cost ; Dopexamine ; High risk patients ; Intensive care ; Morbidity ; Mortality ; Oxygen delivery ; Resource use ; Surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To investigate the cost implications of a treatment policy of a deliberate perioperative increase of oxygen delivery in high risk surgical patients. Design: A cost-effectiveness analysis comparing ‘protocol’ high risk surgical patients in whom oxygen delivery was specifically targeted towards 600 ml/min/m2 with ‘control’ patients. Interventions: In a randomised, controlled clinical trial we previously demonstrated a significant reduction in mortality (5.7% vs 22.2%, p=0.015) and morbidity (0.68±0.16 complications vs 1.35±0.20, p=0.008) in ‘protocol’ high risk surgical patients in whom oxygen delivery was specifically targeted towards 600 ml/min per m2 compared with ‘control’ patients. This current study retrospectively analysed the medical care and National Health Service resource use of each patient in the trial. Departmental purchasing records and business managers were consulted to identify M28.9nthe unit cost of these resources, and thereby the cost of treating each patient was calculated. Results: The median cost of treating a protocol patient was lower than for a control patient (£6,525 vs £7,784) and this reduction was due mainly to a decrease in the cost of treating postoperative complications (median £213 vs £668). The cost of obtaining a survivor was 31% lower in the protocol group. Conclusion: Perioperative increase of oxygen delivery in high risk surgical patients not only improves survival, but also provides an actual and relative cost saving. This may have important implications for the management of these patients and the funding of intensive care.
    Type of Medium: Electronic Resource
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