ISSN:
1432-1106
Schlagwort(e):
Cerebellar unit responses
;
Purkinje cells
;
Click response
;
Mossy fibers
;
Surface negativities
;
Firing patterns
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Summary 1. Unit activities evoked by auditory stimulation in the cerebellar cortex have been studied in the encéphale isolé cat. Poststimulus-time histograms (PSTH) of 1/sec, click-evoked unit discharges have different response patterns with respect to the onset and time course of unit firing. 2. Units have been classified as type I and type II responses based on their preferred firing time relative to the first surface-negative component (N1) of the click evoked folial response. 3. Laminar analysis of the click evoked slow activity centered on an 8–12 msec negative wave in the molecular layer that corresponded with the N1 surface component. An earlier, sharp, negative-positive sequence was found at depths approaching and deep within the granule cell layer. 4. Units considered to be Purkinje cells based on antidromic stimulation or the appearance of typical climbing fiber responses (CFR's) were found exclusively within the type II unit category. Non-identified click units, including various types of cortical interneurons, were found to be either type I or type II units. 5. Evidence that cerebellar click responses are mediated predominately by mossy fiber afferents derives in part from the inhibitory effect of local folial conditioning stimulation upon N1 waves. In addition, the irregular, recurrent CFR's found in click responsive Purkinje cells were temporally unrelated to the acoustic stimulus. Thus click responses in these units appeared to be initiated by mossy fiber activity.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00234380
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