ISSN:
1573-1561
Keywords:
Achillea millefolium
;
mosquito larvicides
;
Aedes triseriatus
;
unsaturated amides
;
N-(2-methylpropyl)-(E,E)-2,4-decadienamide
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract A methanol extract ofAchillea millefolium L. showed activity against 24-hr-old larvae ofAedes triseriatus. Bioassay- and TLC-monitored fractionation yielded a neutral fraction which was refined further by column chromatography to afford the antilarvalN-(2-methlpropyl)-(E,E)-2,4-decadienamide which was identified by spectral methods and through comparisons with a synthesized sample. Isolated and synthesized amides at 5 ppm resulted in 98 and 100% mortality of 24-hr-oldA. triseriatus larvae. TheN-(2-methylpropyl)-amides of decanoic and (E)-2-decenoic acids showed the same order of antilarval activity asN-(2-methylpropyl)-(E,E)-2,4-decadienamide, butN-(2-methylpropyl)sorbamide was inactive.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00987525
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