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Dietary prevention of diabetes in the non-obese diabetic mouse (1988)

Elliott, R. B. ; Reddy, S. N. ; Bibby, N. J. ; [et al.]

Springer

Diabetologia 31 (1988), S. 62-64

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ISSN: 1432-0428

Keywords: NOD mouse ; diabetes ; diet ; casein

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Diabetes prone NOD female mice were fed diets containing different proteins from just before weaning. Only mice receiving meat meal or casein as the protein source developed diabetes at the rate expected from this colony. Lactalbumin and gluten did not precipitate diabetes except in a small number. Casein hydrolysate in lieu of protein protects against overt diabetes, but only if introduced early. The animals which did not show overt diabetes nevertheless had intermittent trace glycosuria and the majority showed mild degrees of peninsular lymphocytic infiltration.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00279136

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