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  • Flow morphometry  (1)
  • Natural cytotoxicity  (1)
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  • 1
    ISSN: 1432-0851
    Schlagwort(e): Interleukin-2 ; Colorectal cancer ; Natural cytotoxicity ; Cytotoxicity
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Natural cytotoxicity (natural killer, NK, and lymphokine-activated killer, LAK, activity) was documented in 12 patients with metastatic colorectal cancer, both before and after a 5-day course of continuous therapy with intravenous recombinant interleukin-2 (rIL-2). Treatment induced a substantial increase in circulating CD56+ lymphocytes (pretreatment: 12.1±6.9%, mean ± SD; posttreatment: 39.2±6.9%. Maximal NK cell activity was induced by treatment with rIL-2 but only suboptimal augmentation of LAK cell cytotoxicity was obtained. This study indicates that although continuous infusion of rIL-2 does have a significant effect on natural cytotoxicity, this is suboptimal and further studies are necessary to define the most efficacious immunity-enhancing regimens of therapy, thereby hopefully improving clinical outcome of rIL-2 treatment.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of volcanology 61 (2000), S. 515-526 
    ISSN: 1432-0819
    Schlagwort(e): Key words Lava flow ; Lava volume ; Lava output ; Mount Etna ; Time series ; Flow morphometry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie
    Notizen: Abstract  A new data set of Etna lava flows erupted since 1868 has been compiled from eight topographic maps of the volcano published at intervals since then. Volumes of 59 flows or groups of flows were measured from topographic difference maps. Most of these volumes are likely to be considerably more accurate than those published previously. We cut the number of flow volumes down to 25 by selecting those examples for which the volume of an individual eruption could be derived with the highest accuracy. This refined data set was searched for high correlations between flow volume and more directly measurable parameters. Only two parameters showed a correlation coefficient of 70% or greater: planimetric flow area A (70%) and duration of the eruption D (79%). If only short duration (〈18 days) flows were used, flow length cubed, L3, had a correlation coefficient of 98%. Using combinations of measured parameters, much more significant correlations with volume were found. Dh had a correlation coefficient of 90% (h is the hydrostatic head of magma above the vent), and  , 92% (where W is mean width and E is the degree of topographic enclosure), and a combination of the two , 97%. These latter formulae were used to derive volumes of all eruptions back to 1868 to compare with those from the complete data set. Values determined from the formulae were, on average, lower by 16% (Dh), 7% ( , and 19% .
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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