ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
MS detection
;
Trace herbicides
;
Natural waters
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary A new method for the simultaneous identification and quantification of base/neutral and acidic pesticides at a low nanogram per liter concentration level in natural waters is presented. The method includes enrichment of the compounds by solid phase extraction on graphitized carbon black, followed by sequential elution of the base/neutral and acidic pesticides. Identification and quantification of the compounds is performed with HPLC-ESI-MS. This procedure involves passing 1 L of ground water and 2 L of drinking water samples through a 0.5 g graphitized carbon black (GCB) extraction cartridge. A conventional 4.6-mm-i.d. reversed phase LC C-18 operating with a 1 mL min−1 flow of the mobile phase was used to chromatograph the analytes. A flow of 100 μL min−1 of the column effluent was diverted to the ESI source. The ESI source was operated in positive ion mode for base/neutral pesticides and in negative-ion mode for acid pesticides. For the analyte considered, the response of the mass detector was linearly related to the amount of the analytes injected between 5 and 250 ng. In all cases, recoveries of the analytes were better than 90%. The limit of detection (signal-to-noise ratio=3) of the method for the pesticides considered in drinking water samples was estimated to be about 3–10 ng L−1.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02466640
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