ISSN:
1741-0444
Keywords:
Drug ejection
;
Micropipettes
;
Neurons
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
Notes:
Abstract A pressurised, pusled, drug ejection system is described. The system uses a laboratory 60 psi (414 kPa) air source, in conjunction with other components, to pressure-eject known amounts of neuroactive chemicals from micropipettes onto tissue cultured neurons. A potential-driven solenoid valve switches the flow on and off, while an electronic pressure transducer, along with associated circuitry, provides parameters of application (pressure amplitude, onset and duration). The pressure switching action has a risetime of 5–10 ms. The quantity of compound ejected can be quantitatively predetermined.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02441528
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