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  • Non-ketotic hyperglycinaemia  (2)
  • 1,3-Dibutyl-l-nitrosourea  (1)
  • Acute autonomic and sensory neuropathy  (1)
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Materialart
Erscheinungszeitraum
Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    Mammary tumorigenic effect of a new nitrosourea, 1,3-dibutyl-l-nitrosourea (B-BNU), in female Donryu rats (1980)
    Springer
    Journal of cancer research and clinical oncology 96 (1980), S. 35-41 
    Details
    ISSN: 1432-1335
    Schlagwort(e): Mammary tumor ; Nitrosourea ; 1,3-Dibutyl-l-nitrosourea ; Donryu rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Four groups (groups 1-4) of female Donryu rats were given continuously 400, 200, 100, or 0 ppm solution of 1,3-dibutyl-1-nitrosourea (B-BNU) as their drinking water, and were studied for the development of tumors. The incidence of mammary tumors was 15/19 (79%), 20/24 (83%), 21/26 (81%), and 8/25 (32%) in groups 1, 2, 3, and 4, respectively. In addition, hematopoietic neoplasms, uterine tumors, and vaginal tumors developed in 13, 11, and six rats, respectively in 69 treated rats. Other tumors were infrequent.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00412895
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Difficulties in assessing the effect of strychnine on the outcome of non-ketotic hyperglycinaemia. Observations on sisters with a mild T-protein defect (1986)
    Springer
    European journal of pediatrics 145 (1986), S. 267-270 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Non-ketotic hyperglycinaemia ; Strychnine ; Glycine cleavage system
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Sisters with a mild variant of non-ketotic hyperglycinaemia resulting from a defect in the T-protein of the glycine cleavage system had different clinical outcomes. The older sister was ascertained at 6 months of age because of mental retardation. She received only brief treatment with sodium benzoate from 11–15 months and at 15 years of age is profoundly retarded and has epilepsy. The younger sister was diagnosed 36h after birth, was treated with strychnine, sodium benzoate and arginine from the neonatal period and at 27 months of age is only moderately retarded and free of seizures. The possible role of strychnine in the improved outcome is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00439398
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Non-ketotic hyperglycinaemia: clinical and biochemical aspects (1987)
    Springer
    European journal of pediatrics 146 (1987), S. 221-227 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Non-ketotic hyperglycinaemia ; Glycine cleavage enzyme
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstracts Non-ketotic hyperglycinaemia is an autosomal recessive disorder of glycine metabolism characterized by elevated concentrations of glycine in plasma, urine and cerebrospinal fluid. The fundamental defect was found to lie in the glycine cleavage system. It is of significance that the major pathway for the catabolism of glycine was elucidated through the studies of hyperglycinaemia. The present knowledge about non-ketotic hyperglycinaemia is described in clinical and biochemical aspects.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00716464
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Acute autonomic and sensory neuropathy: a case report (1990)
    Springer
    Journal of neurology 237 (1990), S. 42-44 
    Details
    ISSN: 1432-1459
    Schlagwort(e): Acute autonomic and sensory neuropathy ; Epstein-Barr virus ; Orthostatic hypotension ; Peripheral neuropathy ; l-Threo-2,3.-dihydroxyphenylserine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A female patient with acute autonomic and sensory neuropathy is described. Urinary disturbance developed rapidly and was followed by orthostatic syncope, absence of lacrimation, salivation and sweating, and sensory impairment. Muscle strength had been consistently normal despite diffuse muscular atrophy. Marked decrease in the number of small myelinated and unmyelinated fibres was revealed in biopsied sural nerve. Eighteen months after the onset, her autonomic symptoms have partially improved.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00319667
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