ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The acidity constants of the six thienyl- and the three phenyl-pyridines, and the stability constants of the corresponding Cu2+ 1:1 complexes were determined in aqueous solution (I = 0.1, NaCIO4; 25°). The basicity of the pyridyl group is increased by a shift of a thienyl or phenyl group in the order 2 〈 3 〈 4 and the influence of the 2′-thienyl group is greater than that of the 3′-thienyl group. The stability of the Cu2+ 1:1 complexes formed with 3- and 4-substituted pyridines is only dependent on their basicity, as is commonly observed for structurally related ligands and their complexes. Due to steric hindrance the complexes of the 2-substituted derivatives are less stable by about 1.5 log units. There is no evidence that the aromatic bonded sulfur of 2-(2′-thienyl)-pyridine participates in complex formation with Cu2+, in opposition to an earlier claim [1].
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19720550233
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