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  • 1
    ISSN: 1432-2307
    Keywords: Paget's disease of bone ; Immunocytochemistry ; Osteoclasts ; Respiratory syncytial virus ; Measles virus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Circumstantial evidence from electron microscopic and immunological studies support the view that Paget's disease of bone represents a slow virus infection. However, there is only limited information available regarding its electron microscopic, enzyme and immunocytochemical characteristics. Two cases were studied using electron microscopy with particular emphasis on the inclusions in osteoclasts. Detailed ultrastructural and cytochemical studies including immuno-electron microscopy were performed. Some osteoclasts demonstrated specific virus-like structures composed of aggregations of microtubules in the nucleus and cytoplasm. The structures were easily digested by trypsin or protease, and were sensitive to RNase, which provided substantial evidence of a proteinaceous nature and inclusion of ribonucleic acid. Immunocytochemical examination identified binding of anti-respiratory syncytial virus and anti-measles virus antibodies in the tissue obtained from one of the two cases examined. The presence of viral antigens in structures in the cytoplasm of Pagetic osteoclasts supports the theory of paramyxovirus involvement in this disease.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of superconductivity 8 (1995), S. 759-764 
    ISSN: 1572-9605
    Keywords: a-axis YBCO ; Rutherford backscattering ; sputtered films
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract Hybrid sputtering and the conventional dc-template sputtering methods were used to deposit highly crystallinea-axis films. The oxygen contents and disorder of the films were measured by the resonant Rutherford backscattering. The oxygen content of the films deposited by the hybrid sputtering depend on the deposition temperature. Films deposited at a low temperature have low oxygen content. The poor superconducting properties of these films may be due to the oxygen deficiency. The stoichiometry of the films deposited by the dc-template sputtering method was found to depend on the microstructure of the template. The disorder at the Ba and O sublattices of these highly crystallinea-axis films are uncorrelated.
    Type of Medium: Electronic Resource
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