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  • 1
    Electronic Resource
    Electronic Resource
    Experimental aspects of an NMR quantum computer with CeP (2000)
    Springer
    Applied physics 70 (2000), S. 359-360 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 03.67.Lx; 76.60.-k; 75.50.Ee
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. An NMR quantum computer based on an integrated device with CeP has been proposed by Yamaguchi and Yamamoto [Appl. Phys. A 68 1 (1999)]. We point out two problems in their scheme. We also investigate experimentally the 31P NMR spectra for our CeP. From the line width, we find that improvement of the sample quality is necessary to satisfy the experimental conditions for a quantum computer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390050060
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of effectiveness of chemotherapy in patients with gastric cancer after curative resection (2000)
    Springer
    International journal of clinical oncology 5 (2000), S. 372-379 
    Details
    ISSN: 1437-7772
    Keywords: Key words p53 ; Gastric cancer ; Adjuvant chemotherapy ; Randomized study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background. A prospective randomized study involving gastric cancer patients was undertaken to evaluate combined adjuvant chemotherapy and the prognostic value of biologic markers. Methods. One hundred and eighty-five patients under 75 years of age who underwent a curable resection of pathologic stage II or III gastric cancer were randomly assigned to receive adjuvant chemotherapy containing either: mitomycin C (MMC) plus oral 5-fluorouracil (FU) (MF), epirubicin plus oral FU (EF), or oral FU (F). Tumor tissue collected at surgery was immunohistochemically analyzed for p53 and proliferating cell nuclear antigen, and DNA ploidy was determined. Results. All prognostic factors were equally distributed in each arm. There was no significant difference among the groups in the 5-year overall survival. When the relationship between the biologic markers and prognosis was analyzed, the overall survival of all patients and stage III patients was poorer in those with p53 positivity, but the difference did not achieve significance. For patients with positive nodes, irrespective of the treatment regimen, p53-positivity was significantly associated with poorer prognosis (P = 0.05). In stage III patients, the survival of those with p53-positivity and DNA aneuploidy was significantly worse than that for patients with any other combination (P = 0.02). Conclusion. No survival benefit was observed with the combined chemotherapeutic regimens compared with FU alone. p53 positivity was negatively correlated to survival for node-positive and stage III patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00012066
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    Paper (German National Licenses)
    Fulltext
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