ISSN:
1435-0130
Keywords:
Intestinal graft
;
PGE1
;
Vascular pedicle ligation
;
Neovascularization
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In this study, prostaglandin E1 (PGE1) was administered daily in a subcutaneous heterotopic jejunal model in rats to compare the results of the viability rate to those in the non-PGE, group. The viability rate of the PGE1 group was 28.6% in the day 5 ligated group, 75.0% in the day 7 ligated group and 100% in the day 14 ligated group. The viability rate of the non-PGE1 group was 0%, 37.5%, and 100%. The results of the PGE1 group in the day 5 and day 7 ligated groups were significantly different from those in the non-PGE1 group. These results indicate that the administration of PGE1 facilitates the neovascularization necessary for survival of the grafted tissue and shortens the time for the graft to become viable at the implantation site.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00210563
Permalink
