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  • Cutaneous candidiasis  (1)
  • PREVALENCE  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 281 (1989), S. 279-283 
    ISSN: 1432-069X
    Keywords: Cutaneous candidiasis ; Epidermal proliferation ; Neutrophils
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A mouse model of cutaneous candidiasis was used to determine if the prominent neutrophilic infiltrates in the infected skin of nonimmune animals were responsible for inducing the early phase of epidermal proliferation seen in these infections. Both the organisms and resulting neutrophilic microabscesses were found in the cellular layers of the epidermis at 12 h after inoculation, and were then extruded together to a more superficial site in the stratum corneum over the next 1–2 days. The degree of epidermal proliferation elicited at the site of the Candida foci, as determined from the thickness of the cellular layers of the epidermis, was the same for foci with neutrophils as for those without, even when the latter came from severely leukopenic animals. The location of neutrophils within the infected skin or the numbers of organisms present did not seem to make a difference with respect to the degree of epidermal proliferation produced at the site of Candida foci. These data suggest that in acute experimental cutaneous Candida infections the organisms can elicit a vigorous epidermal proliferative response in the absence of the neutrophilic infiltrates usually seen in these infections.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 42 (1997), S. 2585-2590 
    ISSN: 1573-2568
    Keywords: IRRITABLE BOWEL SYNDROME ; PREVALENCE ; SELF-REPORTED SYMPTOMS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Although there are several symptomclassification systems for irritable bowel syndrome(IBS), for example, the Manning or Rome criteria, therehas been no previous research on how well theseclassifications correspond to each other or to personsdiagnosed with IBS. We examined data from the DigestiveDisorders Supplement of the 1989 National HealthInterview Survey (NHIS) to assess demographic,socioeconomic, and health status characteristics of two groupsof IBS sufferers — those who met the Manning orRome criteria and those who reported having IBS but didnot meet either criteria. The results showed that the overlap between estimates of IBS and personswith IBS-like symptoms depended on the definition ofIBS. There were socioeconomic differences between thetwo IBS groups and higher rates of functional orwork-related activity limitation and health care utilizationfor all IBS groups relative to US national averages. Insummary, these findings indicate that IBS affects alarge portion of the US population, regardless of the definition used to describe thecondition. Our results suggest that there is a largeundiagnosed population with numerous symptoms consistentwith IBS, but further research is required to determine the differences between people who do and donot seek care, their impact on the health care system,and future therapies to reduce symptomatology andsuffering.
    Type of Medium: Electronic Resource
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