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Synthesis of α- and β-Substituted Aminoethane Sulfonamide Arginine-Glycine Mimics (2000)

Lowik, Dennis W. P. M. ; Liskamp, Rob M. J.

Weinheim : Wiley-Blackwell

Liebigs Annalen 2000 (2000), S. 1219-1228

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ISSN: 1434-193X

Keywords: Peptidomimetics ; Peptidosulfonamides ; Peptidomimetics ; Transition-state isosteres ; Chemistry ; General Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: -In this paper we present a synthesis of both α- and β-substituted aminoethane sulfonamide arginine mimics. The α-substituted sulfonamides were obtained starting from an alkene, whereas the β-substituted sulfonamides were derived from an amino acid derivative.

Additional Material: 1 Ill.

Type of Medium: Electronic Resource

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