ISSN:
1432-2072
Keywords:
Schizophrenia
;
Phenothiazines
;
Reaction
;
Time
;
Symptoms
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A battery of performance tests was administered to acutely ill schizophrenic patients prior to treatment and repeatedly during a 26-week course of treatment with one of three phenothiazines (acetophenazine, chlorpromazine or fluphenazine). Included were measures of simple reaction-time, cognitive stimulus generalization, sway suggestibility, definition of affectively toned words and subjective uncertainty. Each of these measures were chosen to reflect a specific aspect of schizophrenic deficit or dysfunction. Changes in performance over time and correlations with symptom rating scales of psychopathology presumably tapping the same schizophrenic dysfunctions were examined. Most changes in performance occured between the initial and first repeated testing. Correlations with clinical ratings were seen primarily in symptoms of withdrawal and cognitive disturbance.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00402906
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