ISSN:
1612-1112
Keywords:
High-performance hydrophobic interaction chromatography
;
Polyethylene glycol-bonded phases
;
Protein separation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary This paper further investigates the effects of silica base pore size and the molecular weight of polyethylene glycol (PEG) ligands on the coverage of PEG-bonded phases, as well as the resolution of protein separation in high-performance hydrophobic interaction chromatography (HPHIC). The results demonstrate that among the PEG-bonded phases examined in this study, the bonded phase coupled PEG-1500 on LiChrospher 500 silica exhibited the best resolution in protein separation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02324714
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