ISSN:
0021-9304
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
Wear particles released from hip or knee prostheses are known to be involved in the fibrohistiocytic membrane interposed between bone and implant. During surgical treatment for pelvic carcinoma (5 cases) and for isolated pseudomalignant lymphadenopathy (4 cases) lymph nodes in 9 patients who had had lower limb articular replacement were harvested. Light microscopy and image analysis of the nodes showed florid endosinusal histiocytosis, predominant in the cortical area. Using Oil Red O staining and polarized light, metal particles and polyethylene particles were detected in the large histiocytes. Scanning electron microscopy with electron backscattering allowed us to localize metal particles and perform elemental microanalysis. Iron, cobalt, chromium, nickel, zirconium, and barium, known to be used in prosthetic and cementing materials, were identified as component of these particles. Large amounts of polyethylene particles appeared in all cases while metal particles were found to be abundant in only 2 cases. Thus, migration of polyethylene debris from the prosthetic site seems to be the major factor in development of the histiocytes induced in satellite lymph nodes. © 1996 John Wiley & Sons, Inc.
Additional Material:
9 Ill.
Type of Medium:
Electronic Resource
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