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  • 1
    ISSN: 1432-1106
    Keywords: Precentral motor cortex ; Unit recording ; Isometric precision grip ; Force and rate of force change ; Microstimulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The activity of single neurons within the hand area of the precentral motor cortex of primates was recorded during the performance of a maintained precision grip between the thumb and forefinger. The finger opposition forces were exerted against a strain gauge which allowed force changes to be studied under near isometric conditions. Task performance required the generation of a force ramp (the dynamic phase) and thereafter the maintenance of a stable force for one second (the static phase). Intracortical stimulation through the recording electrode was used to verify that the recordings were made from the appropriate somatotopographic area of the motor cortex. From a total of 221 recorded neurons, 76 were found to be either activated or deactivated during performance of the task. Among the 51 activated neurons, most discharged at higher frequencies during the dynamic phase, than during the static phase. The discharge of some of these neurons could be related to both force (F) and rate of force change (df/dt) whereas certain others could only be correlated with df/dt. The change in discharge frequency for these neurons generally occurred prior to the onset of EMG activity. Eight neurons were more active during maintained force than during the force ramp. The discharge frequency could not be correlated with df/dt and only one showed a significant positive relation to force. The change in discharge frequency for these neurons either coincided or occurred after the onset of EMG activity.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 165 (1976), S. 297-306 
    ISSN: 1432-0878
    Keywords: Pineal gland ; Mole ; Yellow-orange autofluorescent material ; Subcommissural organ
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Une étude de la glande pinéale de la Taupe, animal vivant toujours dans une obscurité complète, a été entreprise selon la technique de fluorescence décrite par Falck et al. (1962). Une importante innervation catécholaminergique a été démontrée tandis que la fluorescence jaune — caractéristique des indoleamines-n'a pas été observée. Après omission du traitement par la formaldehyde, de très nombreuses cellules contenant du material autofluorescent (jaune-orange) furent observées. La nature et la fonction de ce material autofluorescent est discutée.
    Notes: Summary The pineal gland of the mole, a mammal which lives in permanent darkness, has been studied using fluorescence histochemistry. An extensive catecholaminergic innervation is demonstrated. A yellow formaldehyde-induced fluorescence, characteristic of indoleamines, was not observed. If formaldehyde vapour treatment was omitted in the procedure, numerous cells containing yellow-orange autofluorescent material could be shown. The nature and possible function of this material is discussed.
    Type of Medium: Electronic Resource
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