ZIB

Hits per page

hit 1 - 1 | 1 hit

Sorting

Electronic Resource

Pharmacokinetics of dextro-, leavo- and racemic propranolol in man (1972)

George, C. F. ; Fenyvesi, T. ; Conolly, M. E. ; [et al.]

Springer

European journal of clinical pharmacology 4 (1972), S. 74-76

add to mindlist on the mindlist

Details

ISSN: 1432-1041

Keywords: Propranolol ; optical isomers

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary Late plasma half-lives of dextro and racemic propranolol were measured in seven adult male subjects after 100 mg taken orally. Mean plasma half-lives of 2.38±0.43 and 2.93±0.63 h were obtained for dextro and racemic preparations respectively. In five of these subjects plasma half-lives after 50 mg dextro and laevo isomers were 2.02±0.53 and 3.20±0.42 h. No difference was found in the rates of absorption of the two isomers It is concluded that these results reflect either differences in distribution or a slower rate of metabolism of the laevo isomer.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00562500

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

hit 1 - 1 | 1 hit