ISSN:
1432-1440
Keywords:
Drug-induced diabetes insipidus
;
Amphotericin B
;
Indomethacin
;
Prostaglandin E2
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Nephrogenic diabetes insipidus (NDI) is a serious side effect of various drugs. Elevated renal prostaglandin E2 levels have been found in patients with lithium-induced NDI and have been implicated in the pathogenesis. We report the case of a patient who developed NDI following treatment with amphotericin B. Prostaglandin levels were elevated. Indomethacin had an antidiuretic effect and normalized prostaglandin levels.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00180544
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