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Protein Biosynthesis: The Codon-Specific Activation of Amino AcidsDedicated to Professor Hermann Hartmann (1978)

Holler, Eggehard

Weinheim : Wiley-Blackwell

Angewandte Chemie International Edition in English 17 (1978), S. 648-656

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ISSN: 0570-0833

Keywords: Protein biosynthesis ; Amino acids ; RNA ; tRNA ; Chemistry ; General Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: At the start of protein biosynthesis the amino acids are chemically activated by esterification with transfer ribonucleic acids bearing the appropriate anticodons. The esterification is catalyzed with an exceptionally high specificity by aminoacyl-tRNA synthetases. Current knowledge of the structural properties of the reactants, the course of the reaction, and the reasons for its specificity are summarized.

Additional Material: 10 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/anie.197806481

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