ISSN:
1432-072X
Keywords:
Alginate
;
Arsenite
;
Inhibition
;
Stimulation
;
Degradation
;
Metabolic inhibitors
;
Pyruvate
;
Pseudomonas aeruginosa
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Biosynthesis of alginic acid in presence of metabolic inhibitors by resting cells of mucoid Pseudomonas aeruginosa was studied. Among the inhibitors tested, arsenite exhibited very interesting results, while the others showed no remarkable-effect. Firstly, arsenite stopped alginate production from all the substrates during initial hours of incubation; secondly, degradation of newly synthesized alginates to smaller molecular weight fragments took place if it was added after a few hours of incubation with the substrate; and thirdly, uncontrolled synthesis of alginate started after several hours of inhibition. Presence of arsenite was needed for the initial inhibitory phase of alginate synthesis; but once the cells were capable of synthesizing alginate after initial hours of inhibition, arsenite may be omitted from the medium.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00470880
Permalink
