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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Clinical and experimental medicine 151 (1969), S. 93-102 
    ISSN: 1591-9528
    Keywords: Rat ; Nephron ; Alkaline Phosphatase ; ATPases ; Quantitative Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary With three phosphohydrolases, i. e. alkaline phosphatase (Na+K+), ATPase and (Mg++) ATPase, a segmentation of the proximal tubule and a marked difference between the short (superficial) and long (Juxtamedullary) nephron is revealed by quantitative histochemistry. With the exception of the superficial nephron of the male rat, alkaline phosphatase activity increases along the proximal tubule independent of sex. (Na+K+) ATPase and (Mg++) ATPase show in both types of nephrons a decrease of activity along the proximal tubule. The juxtamedullary nephron is more active than the superficial. Parallelism of the site of avtivity for alkaline phosphatase and the location of reabsorption of phosphate ions is discussed. Morphological and physiological data from the literature are brought into connexion with the enzymatic changes of a (Na+K+) ATPase activity decrease.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Clinical and experimental medicine 155 (1971), S. 340-353 
    ISSN: 1591-9528
    Keywords: Rat ; Nephron types ; Oxydoreductases ; Quantitative histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary With oxidoreductases mediating several metabolic pathways, e.g. LDH (glycolysis), ICDH, MDH (tricarboxylic acid cycle), GLDH (aminoacid metabolism) and G-6-PDH (hexose monophosphate shunt) additional marked differences between the subcapsular (SCN) and juxtamedullary (JMN) nephron of rat kidney could be established using quantitative histochemical technique. The enzymatic differences between the two nephron types are mainly quantitative as could be shown within the logarithmic network. The intrarenal enzymatic heterogeneity seems to constitute a general concept.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2013
    Keywords: NaKATPase ; Intracellular Localisation ; Proximal Tubule ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary With refinements of quantitative histochemistry, i.e. oilwell technique, enzymaticP ianalysis and NADP/NADPH cycling an enzymatic polarization of the tubular epithelial cell from the rat nephron to NaKATPase can be established. NaKATPase activity is limited to the basal area of the epithelial cell. Brush border fragments lack NaKATPase activity.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 306 (1969), S. 219-226 
    ISSN: 1432-2013
    Keywords: (Na+K+)-ATPase ; (Mg++)-ATPase ; Rat ; Nephron ; Quantitative Histochemistry ; (Na+K+)-ATPase ; (Mg++)-ATPase ; Ratte ; Nephron ; Quantitative Histochemie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In 17 male Wistar rats in antidiuresis 10 different nephron segments and arteries are identified with the aid of Lowry's technique, dissected and total-and (Mg++)-adenosintriphosphatase (=ATPase) determined. (Na+K+)-activated ATPase in the distal tubule is four to five times (max. eight times) more active than in the proximal segment. This difference of activity may speak for a high pump mechanism mediated by the way of a (Na+K+)-activated enzyme system in the distal nephron and for a partially passive reabsorption of sodium from the proximal convolution.
    Type of Medium: Electronic Resource
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