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Digitale Medien

Identification of an autonomously replicating sequence near a histone gene of Physarum polycephalum (1986)

Wilhelm, M. L. ; Demouveau, M. F. ; Wilhelm, F. X.

Springer

Current genetics 10 (1986), S. 459-462

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Details

ISSN: 1432-0983

Schlagwort(e): Ars sequence ; Histone gene ; Replication origin ; Physarum polycephalum

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Summary Fragments of DNA with function as autonomous replication sequences in yeast were cloned from Physarum polycephalum. The ars activity is located in a 1.2 kbp fragment extanding 1.5 kbp to 2.7 kbp upstream of the 5′ end of a histone H4 gene. Our recent finding that a replication origin is located at a distance less than 3 kbp of this histone gene suggests that the ars element identified coincides with a specialized replication origin and can be used to direct chromosome replication in Physarum polycephalum.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00419874

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