ISSN:
1432-2072
Keywords:
Chlorpromazine
;
Pentobarbital
;
Delayed Matching
;
Motor Impairment
;
Sedation
;
Memory
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Monkeys trained to perform in a delayed matching test under five delay conditions were given chlorpromazine hydrochloride (0.05, 0.1, 0.2 and 0.4 mg/kg) and pentobarbital sodium (1.0, 10.0 and 20.0 mg/kg) before test sessions. Both drugs decreased response rate proportionally as dose increased. Chlorpromazine initially depressed accuracy, but showed no specific effects as delay interval increased. Pentobarbital had little effect upon accuracy, although impairment on the simultaneous conditions was seen at the highest dose. It is concluded that neither drug produced specific effects upon short-term memory.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00407045
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