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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 79 (1990), S. 268-272 
    ISSN: 1432-2242
    Keywords: Mice ; Lifetime ; Performance ; Longevity ; Selection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary An experiment was conducted in mice to examine whether selection can increase reproductive life and lifetime production of progeny. Mice in two lines with litter size standardized at birth and in two lines without standardization were pair-mated at 7 weeks of age and maintained as long as they produced litters up to 382 days. Progeny from the sixth litters were used to maintain the four selected lines, while progeny from the first litters were bred to maintain unselected control lines. Selected and control lines were compared at five and six generations of the selected lines. Contemporary comparisons revealed that the length of reproductive life and most lifetime production traits were significantly greater in the selected than in control lines. Realized heritability of the length of reproductive life ranged from 0.08 to 0.13. It was concluded that the length of reproductive life and lifetime production in mice can be increased by selection.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 91 (1995), S. 553-556 
    ISSN: 1432-2242
    Keywords: Coefficient of variation of response ; Genetic drift ; Selection ; Effective-population size ; Short- and long-term
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The minimum population size required for selection in order to reduce the effect of genetic drift to a particular level has been considered. The model of Nicholas was extended to include the measurement-error variance in the response variance. Situations where the sex ratios among scored and breeding individuals are unequal are also considered. When the duration of a selection experiment is relatively long, Nicholas' approximation (i.e., assuming that measurement error is negligible relative to drift) is useful in determining the minimum effective population size required. However, the measurement-error variance becomes an important source of variation in short-term (≤ 5 generations) selection experiments, and should not be ignored.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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