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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 82 (1991), S. 368-378 
    ISSN: 1432-2242
    Keywords: Genetic control ; Simulation ; Translocation ; Inversion ; Genetic sexing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The GENCON simulation program GC5 is designed to simulate genetic population control using field-female killing (FK) systems carying pericentric inversions in addition to Y-linked translocations and deleterious mutations. Homozygous-viable pericentric inversions are included on the same chromosomes as the deleterious mutations, in repulsion to the Y-linked translocation. Released males transmit the inversions and mutations to their daughters and the translocation to their sons. Daughters are semisterile regardless of the type of male they mate with, because products of crossing-over within the inversions carry inviable duplications and deficiencies. Compared to present FK systems, inversion-containing strains give higher levels of genetic death, with both faster initial suppression and greater persistence of genetic death from field-reared descendants if releases are interrupted. At low release rates, both types of FK system are more effective than sterile males.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 82 (1991), S. 33-43 
    ISSN: 1432-2242
    Keywords: Genetic control ; Simulation ; Migration ; Translocation ; Lucilia cuprina
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary An analytical version of the genetic control simulation program GENCON has been used to further analyze the data obtained during field trials of genetic control of the sheep blowfly, Lucilia cuprina, in 1976–79. In the simulations, population trends from a nonrelease area were used as an estimate of the rates of increase that would have occurred in the target population if there had been no releases. Genetic data from the target area (frequencies of matings by released males) were used to predict the frequencies of descendants of released males, the resulting genetic death, and the effects of this on population trends. In simulations that assumed no migration and full survival and competitiveness of all field-reared descendants of released males (translocation-bearing males and males and females heterozygous for deleterious mutations), neither the predicted genetic changes nor the predicted population trends agreed well with the observed data. Further simulations suggested that reduced survival or competitiveness of field-reared descendants did not account for this disagreement, but that immigration of wild flies into the test areas was probably a major contributor to the failure to achieve suppression. However, immigration alone was not sufficient to explain all the differences between observed and expected results. Other plausible contributors to this failure were: (1) lower survival of translocation males due to the effects of a dieldrin resistance allele carried on the translocation, and (2) increased survival of immature stages of L. cuprina at low population densities.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 76 (1988), S. 870-879 
    ISSN: 1432-2242
    Keywords: Genetic control ; Simulation ; Translocation ; Sterile male ; Lucilia cuprina
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A computer program, GENCON, designed to simulate genetic control using field-female killing systems, is described. These systems incorporate sex-linked translocations and conditional lethal mutations. Genetic death in field populations is caused by semisterility of the translocation and by homozygosis of the mutations in females and non-translocation males of field origin. Simulations using the program compare the effectiveness, in populations regulated by density, of genetic control using this type of system with control using sterile-male release. At high release rates, sterile males cause more rapid suppression and earlier eradication than sex-linked translocation strains. However, if releases are interrupted before eradication, the rate of recovery of density-dependent populations is more rapid following sterile-male release than following suppression with translocation strains. In such populations, the cumulative population suppression (number of individuals killed) is greater with translocation-strain release than with sterile-male release. At low release rates, sex-linked translocation strains can be much more effective at suppressing and eradicating density-dependent populations than sterile males. In continental Australia, eradication of the sheep blowfly Lucilia cuprina is probably not practicable. A suppression campaign using sex-linked translocation strains could yield a higher benefit to cost ratio than one using sterile males.
    Type of Medium: Electronic Resource
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