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Immunofluorescent localization of transglutaminase in rat small intestine (1988)

Sharp, Gaynor ; Grindley, Helen ; Lorand, L. ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Cell Biochemistry and Function 6 (1988), S. 137-141

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Details

ISSN: 0263-6484

Keywords: Small intestine ; transglutaminase ; immunohistochemistry ; coeliac disease ; Chemistry ; Biochemistry and Biotechnology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: The distribution of intestinal transglutaminase was investigated by immunofluorescence microscopy using rabbit anti-guinea pig transglutaminase immunoglobulin. Transglutaminase-related antigen was demonstrated principally in the cytoplasm of villous core interstitial cells with some activity in the brush border region of the villous epithelial cells. Implications for the pathogenesis of coeliac disease are discussed.

Additional Material: 3 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/cbf.290060209

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