ISSN:
1432-198X
Keywords:
Congenital nephrotic syndrome
;
Nephrotic syndrome
;
Renal transplant
;
Soluble immune response suppressor
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A boy developed recurrent steroid-responsive nephrotic syndrome following renal transplantation for congenital nephrotic syndrome. The first episode was associated with mild tubulointerstitial rejection on kidney biopsy. Subsequent episodes showed normal histology by light microscopy and epithelial foot process fusion on electron microscopy, consistent with minimal change nephrotic syndrome. Serum analysis for soluble immune response suppressor was negative pre-nephrectomy, positive during each bout of nephrotic syndrome, and negative during each remission. This case represent de novo occurrence of steroid-sensitive minimal change nephrotic syndrome following renal transplantation for congenital nephrotic syndrome. We stress the need for histological examination of the renal allograft to diagnose rejection, recurrent disease, or de novo disease.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00867484
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