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  • Splenic autotransplantation  (1)
  • 1
    ISSN: 1435-2451
    Keywords: Splenic autotransplantation ; Immune reaction ; Perfusion ; Pig ; Autologe Milztransplantation ; Immunreaktion ; Durchblutung ; Schwein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Diese Studie beschreibt quantitativ Immunvorgänge und die Durchblutungsrate von Milzregeneraten nach Autotransplantation von Milzgewebe in das Omentum majus. Das Gewicht und die Perfusion der Transplantate 12 Monate postop. waren deutlich reduziert. Die Anzahl der Antikörper-produzierenden Zellen in den Transplantaten war im Vergleich zur normalen Milz nur gering vermindert, während die Milzregenerate das Serum-IgM-Defizit nach Splenektomie nach 4 Monaten ausglichen. Weiters fanden wir verschiedene Proliferationsraten für B- und T-Lymphocyten in den Transplantaten und der normalen Milz nach Mitogenstimulation.
    Notes: Summary The study deals with the immunological capacity and perfusion rate of splenic grafts in pigs after autologous transplantation into the omentum majus. 12 months after operation the weight and relative blood flow of the regenerated splenic tissue were clearly reduced. The number of antibody forming cells in the grafts was only slightly decreased compared to the normal spleen, whereas the autotransplants could balance a serum-IgM-deficiency, observed due to splenectomy, 4 months after grafting. Furthermore the mitogenic stimulation of T- and B-lymphocytes showed different proliferation rates for the autotransplants compared to the spleen.
    Type of Medium: Electronic Resource
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