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Attenuation of endothelium-dependent relaxation in mesenteric artery during noise-induced hypertension (1993)

Wu, C. C. ; Chen, S. J. ; Yen, M. H.

Springer

Journal of biomedical science 1 (1993), S. 49-53

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ISSN: 1423-0127

Keywords: Noise ; Endothelium ; A23187 ; Acetylcholine ; Nitroglycerin

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Abstract The present study was designed to determine whether there is a causal relationship between noise-induced hypertension and changes of endothelial function. Rats were exposed to noise stress (100 dB, 1 kHz, 4 h/day, 6 days/week) for 1–4 weeks. The systolic blood pressure was significantly increased after rats were exposed to noise stress for 3 weeks. The relaxant responses of isolated mesenteric arterial rings to endothelium-dependent vasodilators (A23187 and acetylcholine) in noise-treated rats were significantly less than those in control rats. This difference in response to acetylcholine still existed in the presence of methylene blue or Nω-nitro-L-arginine. On the other hand, the responses to the endothelium-independent vasodilator nitroglycerin were not affected in rats exposed to noise stress. The attenuation to endothelium-dependent vasodilators during noise stress may result in increasing peripheral vascular resistance and thus elevate blood pressure. This indicates that noise-induced hypertension may be partly due to the alterations of endothelial activity.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02258339

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P-V-T properties of alternating poly(ethylene-propylene) liquids (1994)

Chen, S.-j. ; Chiew, Y. C. ; Gardecki, J. A. ; [et al.]

Bognor Regis [u.a.] : Wiley-Blackwell

Journal of Polymer Science Part B: Polymer Physics 32 (1994), S. 1791-1798

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ISSN: 0887-6266

Keywords: alternating poly(ethylene-propylene) (hydrogenated polyisoprene) melts ; pressure-volume-temperature (P-V-T) properties ; density ; specific volume ; equations of state ; Flory-Orwoll-Vrij (FOV) ; Modified Cell Model (MCM) ; Sanchez-Lacombe (SL) ; Statistical Associating Fluid Theory (SAFT) ; Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Physics

Notes: The pressure-volume-temperature (P-V-T) properties of monodisperse alternating poly(ethylene-propylene) (hydrogenated polyisoprene) melts of varying molecular weights are measured at 0.1 MPa 〈 P 〈 200.1 MPa, and 290 K 〈 T 〈 510 K in a dilatometer-type apparatus. The Flory-Orwoll-Vrij (FOV), Modified Cell Model (MCM), Sanchez-Lacombe (SL), and the Statistical Associating Fluid Theory (SAFT) equations of state are found to correlate the experimental data with excellent accuracy, except either at low pressures and high temperatures, or at high pressures and low temperatures. On average, MCM and SAFT fit the data slightly better than FOV and SL. The equation-of-state parameters are found to be independent of molecular weight, especially for SAFT, as required by the theory. © 1994 John Wiley & Sons, Inc.

Additional Material: 6 Ill.