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Digitale Medien

The effect of orally administered cocaine on sleep of depressed patients (1974)

Post, R. M. ; Gillin, J. C. ; Wyatt, R. J. ; [weitere]

Springer

Psychopharmacology 37 (1974), S. 59-66

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Details

ISSN: 1432-2072

Schlagwort(e): Cocaine ; Stimulants ; Depression ; Sleep ; Dreaming ; Electroencephalograph

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Cocaine was administered orally on a double-blind basis to depressed patients and effects on EEG-monitored sleep were assessed. In doses which did not produce consistent effects on vital signs or mood, cocaine significantly reduced total sleep and rapid eye movement (REM) sleep. The REM sleep supression with cocaine administration and rebound upon cocaine discontinuation was dose related; there was a greater effect at higher doses. Two properties of cocaine appear to closely correspond to those of many other drugs which suppress REM sleep in man—enhancement of functional catecholamines and/or high drug-abuse potential.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00426683

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