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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 226 (1982), S. 579-588 
    ISSN: 1432-0878
    Keywords: Synapses ; Vesicles, microtubules ; Microtubule labilities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The microtubules in different parts of the neuron and synaptosomes were examined with respect to their stability, structure and orientation. On the basis of distribution, different labilities and differences in protofilament substructure seen by tannic acid staining, we have classified microtubules into eight major categories. Functional involvements in vesicle translocation, cytoskeletal support and the regulation of assembly/disassembly are considered.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 231 (1983), S. 93-102 
    ISSN: 1432-0878
    Keywords: Synapses ; Microtubules ; Presynaptic dense projections ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Using techniques for enhanced microtubular preservation (albumin pretreatment of Gray) occipital and pyriform cortices of rats were studied by electron microscopy at various stages of development. A close structural relationship was seen between microtubules (mts), focal membrane densities, synaptic vesicles, and presynaptic dense projections (pre-dps) during maturation. Mts were seen in the neonates to be focused onto the inner surface of immature axonic profiles merging or sometimes fragmenting there. Focal densities occur at these attachment sites and thereafter synaptic vesicles clothe the mts and abut onto these presumed primordial pre-dps. Thus, mts may contribute to the initial formation of pre-dps as well as their maintenance in the adult and may act to channel the first synaptic vesicles to the site of eventual synaptic contact and transmitter release.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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