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  • 1
    Electronic Resource
    Electronic Resource
    Deanol in the treatment of tardive dyskinesia (1977)
    Springer
    Psychopharmacology 52 (1977), S. 257-261 
    Details
    ISSN: 1432-2072
    Keywords: Tardive dyskinesia ; Deanol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ten hospitalized chronic psychotic patients with symptoms of tardive dyskinesia were given deanol and placebo, each for 8 weeks following a double blind, crossover design. No psychotropic agents were administered during the trial. Improvement occurred in all patients during the first treatment phase regardless of which drug the patients received; seven patients were on deanol and three on placebo during this time. The possible reasons for this decrease were discussed. It was concluded that deanol may have contributed to the decline but that its effect on the disorder was not dramatic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00426709
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Clozapine in tardive dyskinesia (1978)
    Springer
    Psychopharmacology 56 (1978), S. 75-80 
    Details
    ISSN: 1432-2072
    Keywords: Clozapine ; Schizophrenia ; Tardive dyskinesia ; Parkinsonism ; Neutropenia ; Convulsions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Clozapine, which has had limited clinical testing in the U.S.A., was evaluated in 12 chronic schizophrenic patients with tardive dyskinesia. Its antipsychotic activity was again demonstrated and it suppressed the symptoms of tardive dyskinesia with a marked rebound occurring in these symptoms when it was withdrawn; there was no rigidity or other Parkinsonian symptoms. However, out of a total of 12 patients, neutropenia (800 and 1120) occurred in two patients, convulsions in one patient, marked withdrawal effects in three patients, and a hypotensive collapse with atrial fibrillation in one patient. If these adverse effects are confirmed in a larger sample size, then despite the novel desirable effects of clozapine it would seem unlikely that it will gain widespread or routine use1.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00571412
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Tardive dyskinesia and psychotropic drug history (1978)
    Springer
    Psychopharmacology 58 (1978), S. 117-124 
    Details
    ISSN: 1432-2072
    Keywords: Tardive dyskinesia ; Neuroleptics ; Dosage ; Sex ; Age
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The adult population of a large mental hospital was screened for tardive dyskinesia (TD). Approximately 11% of the hospital population showed signs of TD; females and the elderly were over-represented in the TD group. A representative sample of those with TD was selected and a control (non-TD) patient was chosen to match each of the TD subjects in age, sex, length of hospitalization, diagnosis, and race. The charts of these subjects were searched for any indices of brain damage and the complete psychotropic medication history was recorded. There was no difference between the TD and controls in the amount of psychotropics ingested, in the duration of administration, in the kinds of drugs, or in the organicity history. Women as a group, however, tended to have more polypharmacy than men. The role of neuroleptics in TD is discussed as well as other possible etiological factors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00426893
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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