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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 44 (1988), S. 990-991 
    ISSN: 1420-9071
    Keywords: Cytochrome P-450 ; ecdysone 20-monooxygenase ; juglone ; plumbagin ; steroid hydroxylase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The chitin synthetase inhibitor plumbagin and its 2-demethyl derivative juglone were found to inhibit in a dose-response fashion the cytochrome P-450 dependent ecdysone 20-monooxygenase activity associated with adult femaleAedes aegypti, wandering stage larvae ofDrosophila melanogaster, and fat body and midgut from last instar larvae ofManduca sexta. The concentration of these naphthoquinones required to elicit a 50% inhibition of the steroid hydroxylase activity in all the insects was approximately 1×10−4 M.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1420-9071
    Keywords: Adenylate cyclase ; cytochrome P-450 ; ecdysone 20-monooxygenase ; forskolin ; steroid hydroxylase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The adenylate cyclase activator forskolin and its pharmacologically inactive derivative 1,9-dideoxyforskolin were found to inhibit in a dose-dependent fashion the ecdysone 20-monooxygenase activity associated with wandering stage larvae ofDrosophila melanogaster and fat body and midgut from last instar larvae of the tobacco hornworm,Manduca sexta. The concentrations of these labdane diterpenes required to elicit a 50% inhibition of the cytochrome P-450 dependent steroid hydroxylase activity in the insect tissues ranged from approximately 5×10−6 to 5×10−4 M.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of anthropology 8 (1993), S. 259-279 
    ISSN: 1824-3096
    Keywords: hand bones ; anthropometry ; pattern profile analysis ; Ten State Nutrition Survey
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract This study utilizes radiographic samples of white, black. Mexican-American, and Asian males and females from the Ten State Nutrition Survey to examine the degree and pattern of variation seen in measurements of bones from the three radial hand rays. Pattern profile analysis is used to portray graphically the intersample differences for 44 length and width variables. This technique allows a visual assessment of intersample differences and extends results of statistical analyses. Base widths serve best in separating male and female groups. Males have a longer first ray with respect to the second ray and a longer first proximal phalanx compared with the second proximal phalanx than do females. Certain ray III variables seem to hold the most promise for separating samples within one sex. Correlation of pattern profile curves demonstrates that within nonwhite ethnic samples the shape of male and female curves is similar when plotted against the white reference samples. Coefficients of variation for the large white samples are highest for mid-widths and tuft widths of distal phalanges and lowest for lengths and base widths of proximal phalanges II and III. While some of the variation between groups may serve to distinguish populations and may relate broadly to evolutionary history, it is difficult to show clear functional correlates for the majority of the variation detected. It is suggested that hypotheses relating morphology of hominid hands to hand function and behavior should consider the extent of modern human hand bone variation.
    Type of Medium: Electronic Resource
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