Digitale Medien
Springer
European journal of pediatrics
153 (1994), S. 241-244
ISSN:
1432-1076
Schlagwort(e):
Testotoxicosis Precocious puberty
;
Suppressed gonadotrophins
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Abstract We report two cases of ‘familial testotoxicosis’ in a family of Southern Chinese descent. The proband, an 8-year 4-month-old boy and his 35-year-old father both presented with early sexual development. In both cases the testicular volume was only 6 ml despite fully developed secondary sexual characteristics. Both patients had adult testosterone concentrations but a suppressed gonadotrophin response to gonadotrophin-releasing hormone. The suppressed gonadotrophin response to gonadotrophin-releasing hormone in the father suggests that autonomous gonadal production of sex steroid by the testes can persist well into adult life in some patients with familial testotoxicosis.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01954510
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