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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 247 (1990), S. 352-355 
    ISSN: 1434-4726
    Keywords: Tympanic membrane ; Perforation ; Healing process ; Epithelial migration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The healing process in 10 human tympanic membrane perforations after trauma and 20 myringotomies was observed under the microscope and was photographed. The movement of the healing process was from the central portion of the perforation to the periphery and followed the same direction as the drum's epitehlial migration. At the central portion of the perforation's margin, the keratin layer proceeded to the periphery and was followed by the epidermal cell layer. Only slight movement was observed at the peripheral portion of the perforation. Histopathological examination confirmed these observations. These findings demonstrate that epithelial migration on the tympanic membrane plays a great role in the healing of a perforation.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 243 (1986), S. 39-42 
    ISSN: 1434-4726
    Keywords: Epithelial migration ; Tympanic membrane ; External canal ; Pathology ; Cholesteatoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An ink dot staining method was used to examine epithelial migration in normal ears, in pathologic tympanic membranes, and in external auditory canal cholesteatoma. The direction of the epithelial migration was found to coincide with that of the vessels in normal ears. This suggested that epithelial migration was controlled by the vessels which supply the epidermal layer of the tympanic membrane. In pathologic tympanic membranes and external auditory canal cholesteatomas, epithelial migration was disturbed to various degrees and depended on the local conditions. In these pathologic conditions, the tympanic membrane showed less vascularization. Based on our findings, we believe that a poor blood supply is the major etiologic factor for the epithelial migratory disturbances of the tympanic membrane.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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